Antimicrobial discovery and drug development – RSC Podcast
January 26, 2023
How do we develop drugs like antibiotics? How long does it take for such a drug to go from its inception in a research lab to use in a…
World Antibiotic Awareness Week Video
November 18, 2019
News,Alderley Park,Publications
This week is World Antibiotic Awareness Week.
Industry group calls for action over £500m funding gap on AMR
November 16, 2018
A life science industry report representing 36 key businesses and organisations concerned about the growing impact of anti-microbial…
Podcast: Tackling The AMR Crisis
July 30, 2018
In this podcast Mike Ward of Informa talks to Dr Peter Jackson, executive director of the AMR Centre.
Publications authored by Infex Therapeutics scientists:
- WO 2019/220125 “Antibacterial compounds” (Published 21 Nov 2019, https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2019220125)
- WO 2021/099793 “1-Aminosulfonyl-2-carboxypyrrole derivatives as metallo-beta-lactamase inhibitors” (Published 27 May 2021, https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2021099793)
- N Ooi, V E Lee, N Chalam-Judge, R Newman, A J Wilkinson, I R Cooper, D Orr, S Lee and V J Savage. Restoring carbapenem efficacy: a novel carbapenem companion targeting metallo-β-lactamases in carbapenem-resistant Enterobacterales. Journal of Antimicrobial Chemotherapy 2021; 76(2): 460–466. https://doi.org/10.1093/jac/dkaa455
- WO 2022/074385 “Synthesis of pyrrole acid derivatives” (Published 14 Apr 2022, https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2022074385)
- GB2602096A “Compounds: Sulfamoyl-pyrrole and sulfamoyl-pyrazole compounds and their use in treating bacterial infections” (Published 22 Jun 2022, https://worldwide.espacenet.com/patent/search?q=pn%3DGB2602096A)
- A J Wilkinson, N Ooi, J Finlayson, V E Lee, D Lyth, K S Maskew, R Newman, D Orr, K Ansell, K Birchall, P Canning, P Coombs, L Fusani, E McIver, J Pisco, P M Ireland, C Jenkins, I H Norville, S J Southern, R Cowan, G Hall, C Kettleborough, V J Savage, I R Cooper. Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors. Bioorganic & Medicinal Chemistry Letters 2023; 90: 129331-129338. https://doi.org/10.1016/j.bmcl.2023.129331
Links:
- Europe gears up for stremlined patent system: https://www.chemistryworld.com/news/europe-gears-up-for-streamlined-patent-system/4016511.article